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NHE-3 PROTEIN
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DeCS
Descriptor
English
:
Sodium-Hydrogen Exchanger 3
Descriptor
Spanish
:
Intercambiador 3 de Sodio-Hidrógeno
Descriptor
Portuguese
:
Trocador 3 de Sódio-Hidrogênio
Synonyms
English
:
NHE 3 Protein
NHE-3 Protein
Na(+)-H(+) Exchanger 3
SLC9A3 Protein
Sodium Hydrogen Exchanger 3
Solute Carrier Family 9 Member 3
Tree Number:
D12.776.157.530.450.162.775.750
D12.776.157.530.937.703.750
D12.776.543.550.190.775.750
D12.776.543.585.450.162.775.750
D12.776.543.585.937.828.750
Definition
English
:
A sodium-hydrogen antiporter expressed primarily by
EPITHELIAL CELLS
in the
kidneys
, it localizes to the apical membrane of the PROXIMAL
KIDNEY
TUBULE, where it functions in
sodium
and water reabsorption and possibly
calcium
homeostasis
. It also is expressed in heart, brain, and lung
tissues
and is resistant to
AMILORIDE
inhibition.
History Note
English
:
2018 (1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57085
Unique Identifier:
D000074083
Occurrence in VHL
:
Similar:
DeCS